翻訳と辞書 Words near each other ・ Mhangura Airport ・ Mhapan ・ Mhar Monastery ・ Mhasad ・ Mhasala taluka ・ Mhasane ・ Mhasin Fadlalla ・ Mhasla ・ Mhasoba ・ Mhasurne ・ Mhaswad ・ Mhaswad Dam ・ Mhaydseh ・ MHC ・ MHC class I ・ MHC class I polypeptide-related sequence A ・ MHC class I polypeptide-related sequence B ・ MHC class II ・ MHC Dmitrov ・ MHC Krylya Sovetov ・ MHC Martin ・ MHC multimer ・ MHC restriction ・ MHD ・ MHDYS ・ MHealth ・ Mhee Noi ・ Mheer ・ MHEG-5 ・ Mheibes Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MHC class I polypeptide-related sequence A ： ウィキペディア英語版 MHC class I polypeptide-related sequence A MHC class I polypeptide-related sequence A (MICA) is a cell surface glycoprotein encoded by the ''MICA'' gene located within MHC locus. MICA is related to MHC class I and has similar domain structure, which is made up of external α1α2α3 domain, transmembrane segment and C-terminal cytoplasmic tail.〔 However, MICA is not associated with β2-microglobulin nor binds peptides as conventional MHC class I molecules do. MICA rather functions as a stress-induced ligand for NKG2D receptor. For example, the heat shock stress pathway is involved in the regulation of MICA expression as transcription of MICA is regulated by promoter heat shock element.〔 MICA is broadly recognized by NK cells, γδ T cells, and CD8+ αβ T cells which carry NKG2D receptor on their cell surface. As a result of NKG2D-MICA engagement, effector cytolytic responses of T cells and NK cells against epithelial tumor cells expressing MICA are initiated.〔 == See also == * MHC class I * Major histocompatibility complex * MICB 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MHC class I polypeptide-related sequence A」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.